MTRF1 Antibody

CATALOG NUMBER: 59-226

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This MTRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-259 amino acids from the Central region of human MTRF1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
52 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MTRF1
Additional Names:
Peptide chain release factor 1, mitochondrial, MRF-1, MtRF-1, MTRF1
Protein Accession Number:
O75570
Ncbi Gene Id Number:
9617
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene was determined by insilico methods to be a mitochondrial protein with similarity to thepeptide chain release factors (RFs) discovered in bacteria andyeast. The peptide chain release factors direct the termination oftranslation in response to the peptide chain termination codons.Initially thought to have a role in the termination of mitochondriaprotein synthesis, a recent publication found no mitochondrialtranslation release functionality. Multiple alternatively splicedtranscript variants have been suggested by mRNA and EST data;however, their full-length natures are not clear. [provided byRefSeq].
Background Reference 1:
Antonicka, H., et al. Am. J. Hum. Genet. 87(1):115-122(2010)
Background Reference 2:
Nozaki, Y., et al. Genes Cells 13(5):429-438(2008)
Background Reference 3:
Soleimanpour-Lichaei, H.R., et al. Mol. Cell 27(5):745-757(2007)
Background Reference 4:
Hansen, L.L., et al. Cytogenet. Cell Genet. 88 (1-2), 91-92 (2000) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-226

List Size:
400 ul

List Price:

$495.00

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