MTUS1 Antibody

CATALOG NUMBER: 61-239

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This MTUS1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 983-1017 amino acids from human MTUS1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:2000
Predicted Molecular Weight:
141 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MTUS1
Additional Names:
Microtubule-associated tumor suppressor 1, AT2 receptor-binding protein, Angiotensin-II type 2 receptor-interacting protein, Mitochondrial tumor suppressor 1, MTUS1, ATBP, ATIP, GK1, KIAA1288, MTSG1
Protein Accession Number:
Q9ULD2
Protein Gi Number:
158706128
Ncbi Gene Id Number:
57509
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth.
Background Reference 1:
Kinjo T.,et al.J. Hum. Genet. 45:12-17(2000).
Background Reference 2:
Seibold S.,et al.FASEB J. 17:1180-1182(2003).
Background Reference 3:
Nouet S.,et al.J. Biol. Chem. 279:28989-28997(2004).
Background Reference 4:
Ota T.,et al.Nat. Genet. 36:40-45(2004).

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

61-239

List Size:
200 ul

List Price:

$495.00

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