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Western blot analysis in MDA-MB435 cell line lysates (15ug/lane).This demonstrates the detected MUTED protein (arrow).
Western blot analysis in mouse bladder tissue lysates (15ug/lane).This demonstrates the detected MUTED protein (arrow).
MUTED Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in MDA-MB435 cell line lysates (15ug/lane).This demonstrates the detected MUTED protein (arrow).

MUTED Antibody

CATALOG NUMBER: 55-052

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Homology:
Predicted species reactivity based on immunogen sequence: Pig
Immunogen:
This MUTED antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-68 amino acids from the Central region of human MUTED.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
Predicted Molecular Weight:
22 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
BLOC1S5
Additional Names:
Biogenesis of lysosome-related organelles complex 1 subunit 5, BLOC-1 subunit 5, Protein Muted homolog, BLOC1S5, MUTED
Protein Accession Number:
Q8TDH9
Protein Gi Number:
34582369
Ncbi Gene Id Number:
63915
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a component of BLOC-1 (biogenesis oflysosome-related organelles complex 1). Components of this complexare involved in the biogenesis of organelles such as melanosomesand platelet-dense granules. A mouse model for Hermansky-PudlakSyndrome is mutated in the murine version of this gene. Alternativesplicing results in multiple transcript variants. Read-throughtranscription exists between this gene and the upstream EEF1E1(eukaryotic translation elongation factor 1 epsilon 1) gene, aswell as with the downstream TXNDC5 (thioredoxin domain containing5) gene.
Background Reference 1:
Morris, D.W., et al. Biol. Psychiatry 63(1):24-31(2008)
Background Reference 2:
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
Background Reference 3:
Starcevic, M., et al. J. Biol. Chem. 279(27):28393-28401(2004)
Background Reference 4:
Li, W., et al. Nat. Genet. 35(1):84-89(2003)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-052

List Size:
400 ul

List Price:

$495.00

Datasheet
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