MXD3 Antibody

CATALOG NUMBER: 27-286

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MXD3.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
MXD3 antibody can be used for detection of MXD3 by ELISA at 1:312500. MXD3 antibody can be used for detection of MXD3 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Tranfected 293T Cell Lysate
Predicted Molecular Weight:
23 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store MXD3 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
MXD3
Additional Names:
MXD3, MYX, MAD3, BHLHC13
Protein Accession Number:
NP_112590
Protein Gi Number:
13775222
Ncbi Gene Id Number:
83463
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
MXD3 contains 1 basic helix-loop-helix (bHLH) domain. It is a transcriptional repressor and binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.
Background Reference 1:
Suzuki, Y., Gene 200 (1-2), 149-156 (1997).

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

27-286

List Size:
100 ul

List Price:

$473.00

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