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Western blot analysis in K562 cell line lysates (35ug/lane).
Western blot analysis in K562 cell line lysates (35ug/lane).

MXD3 Antibody

CATALOG NUMBER: 58-274

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This MXD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the N-terminal region of human MXD3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
23 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MXD3
Additional Names:
Max dimerization protein 3, Max dimerizer 3, Class C basic helix-loop-helix protein 13, bHLHc13, Max-associated protein 3, Max-interacting transcriptional repressor MAD3, Myx, MXD3, BHLHC13, MAD3
Protein Accession Number:
Q9BW11
Protein Gi Number:
74733390
Ncbi Gene Id Number:
83463
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the Myc superfamily of basichelix-loop-helix leucine zipper transcriptional regulators. Theencoded protein forms a heterodimer with the cofactor MAX whichbinds specific E-box DNA motifs in the promoters of target genesand regulates their transcription. Disruption of the MAX-MXD3complex is associated with uncontrolled cell proliferation andtumorigenesis. Transcript variants of this gene encoding differentisoforms have been described.
Background Reference 1:
Barisone, G.A., et al. Cell Cycle 7(4):423-427(2008)
Background Reference 2:
Yun, J.S., et al. Mol. Cell. Biol. 27(23):8178-8189(2007)
Background Reference 3:
Hurlin, P.J., et al. Semin. Cancer Biol. 16(4):265-274(2006)
Background Reference 4:
Sommer, A., et al. J. Biol. Chem. 273(12):6632-6642(1998)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-274

List Size:
400 ul

List Price:

$495.00

Datasheet
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