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Western Blot at 1:2000 dilution + human lung lysate Lysates/proteins at 20 ug per lane.
Western blot analysis in mouse heart tissue lysates (35ug/lane).
Western Blot at 1:2000 dilution + human lung lysate Lysates/proteins at 20 ug per lane.

MXI1 Antibody

CATALOG NUMBER: 58-142

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This MXI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-82 amino acids from the Central region of human MXI1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
26 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MXI1
Additional Names:
Max-interacting protein 1, Max interactor 1, Class C basic helix-loop-helix protein 11, bHLHc11, MXI1, BHLHC11
Protein Accession Number:
P50539
Protein Gi Number:
116242666
Ncbi Gene Id Number:
4601
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Expression of the c-myc gene, which produces an oncogenictranscription factor, is tightly regulated in normal cells but isfrequently deregulated in human cancers. The protein encoded bythis gene is a transcriptional repressor thought to negativelyregulate MYC function, and is therefore a potential tumorsuppressor. This protein inhibits the transcriptional activity ofMYC by competing for MAX, another basic helix-loop-helix proteinthat binds to MYC and is required for its function. Defects in thisgene are frequently found in patients with prostate tumors. Threealternatively spliced transcripts encoding different isoforms havebeen described. Additional alternatively spliced transcripts mayexist but the products of these transcripts have not been verifiedexperimentally.
Background Reference 1:
Lofstedt, T., et al. Exp. Cell Res. 315(11):1924-1936(2009)
Background Reference 2:
Baranzini, S.E., et al. Hum. Mol. Genet. 18(4):767-778(2009)
Background Reference 3:
Tsao, C.C., et al. Cancer Biol. Ther. 7(10):1619-1627(2008)
Background Reference 4:
Suo, X.H., et al. Zhonghua Xue Ye Xue Za Zhi 28(11):745-749(2007)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-142

List Size:
400 ul

List Price:

$495.00

Datasheet
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