MYB Antibody

CATALOG NUMBER: 57-402

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This MYB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 419-448 amino acids from the Central region of human MYB.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
72 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MYB
Additional Names:
Transcriptional activator Myb, Proto-oncogene c-Myb, MYB
Protein Accession Number:
P10242
Protein Gi Number:
2815504
Ncbi Gene Id Number:
4602
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a transcription factor that is a memberof the MYB family of transcription factor genes. The proteincontains three domains, an N-terminal DNA-binding domain, a centraltranscriptional activation domain and a C-terminal domain involvedin transcriptional repression. This protein plays an essential rolein the regulation of hematopoiesis and may play a role intumorigenesis. Alternative splicing results in multiple transcriptvariants.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Tanno, B., et al. J. Biol. Chem. 285(38):29434-29445(2010)
Background Reference 3:
Melen, E., et al. J. Allergy Clin. Immunol. 126(3):631-637(2010)
Background Reference 4:
Stenman, G., et al. Cell Cycle 9(15):2986-2995(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-402

List Size:
400 ul

List Price:

$495.00

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