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Myostatin Propeptide Recombinant Protein

CATALOG NUMBER: 40-210

Specifications
source-species:
E. coli
Species:
Human
source-species:
E. coli
Recombinant Protein Sequence:
MNENSEQKEN VEKEGLCNAC TWRQNTKSSR IEAIKIQILS KLRLETAPNI SKDVIRQLLP KAPPLRELID QYDVQRDDSS DGSLEDDDYH ATTETIITMP TESDFLMQVD GKPKCCFFKF SSKIQYNKVV KAQLWIYLRP VETPTTVFVQ ILRLIKPMKD GTRYTGIRSL KLDMNPGTGI WQSIDVKTVL QNWLKQPESN LGIEIKALDE NGHDLAVTFP GPGEDGLNPF LEVKVTDTPK RSRR
Biological Activity:
Biological activity was determined by its ability to neutralize the Myostatin inhibitory effect of murine MPC - 11 cells. The expected ED50is 0.01 - 0.04 μg/mL in the presence of 50 ng/mL Myostatin.
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized Myostatin Propeptide recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Myostatin Propeptide is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing Myostatin Propeptide recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
MSTN
Additional Names:
GDF8, MSLHP, GDF8, Myostatin, GDF-8
Protein Accession Number:
NP_005250.1
Protein Gi Number:
4885259
Ncbi Gene Id Number:
2660
Background:
Mature Myostatin is obtained by proteolytic processing of a biologically-inactive precursor protein, which contains an N-terminal propeptide of 243 amino acid residues. Myostatin Propeptide exhibits high binding affinity for myostatin and has been shown to be a potent inhibitor of Myostatin. Over-expression of myostatin propeptide in mice resulted in large increases (up to 200%) in skeletal muscle mass, similar to those observed in Myostatin knockout mice. Recombinant Human Myostatin Propeptide is a 27.8 kDa protein consisting of 244 amino acid residues.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-210

List Size:
0.005 mg, 0.025 mg

List Price:

Price range: $215.00 through $323.00

Datasheet
Shipping Info

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