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MYT1 (phospho Ser83) Antibody

CATALOG NUMBER: 79-858

Clonality:
Polyclonal
Tested Applications:
IHC
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
MYT1 (phospho Ser83) antibody was raised against a peptide sequence around phosphorylation site of Serine 83 (R-V-S (p)-F-R) derived from Human MYT1.
Conjugate:
Unconjugated
Tested Applications:
IHC
Specificity:
The antibody detects endogenous levels of MYT1 only when phosphorylated at serine 83.
Predicted Molecular Weight:
54 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
PKMYT1
Additional Names:
PMYT1, PKMYT1, MYT1 kinase
Protein Accession Number:
XP_006721039.1
Protein Gi Number:
33383241
Ncbi Gene Id Number:
9088
Background:
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Background Reference 1:
Booher R.N., J. Biol. Chem. 272:22300-22306(1997).
Background Reference 2:
Liu F., Mol. Cell. Biol. 17:571-583(1997).
Background Reference 3:
Nousiainen M., Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006).

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-858

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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