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Western blot analysis of NALP11 in HeLa cell lysate with NALP11 antibody at 1 μg/mL.
Immunocytochemistry of NALP11 in HeLa cells with NALP11 antibody at 2.5 μg/mL.
Immunofluorescence of NALP11 in HeLa cells with NALP11 antibody at 20 μg/mL.
Western blot analysis of NALP11 in HeLa cell lysate with NALP11 antibody at 1 μg/mL.
Trial Size

NALP11 Antibody

CATALOG NUMBER: 5969

Clonality:
Polyclonal
Tested Applications:
ELISA, ICC, IF, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
NALP11 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human NALP11.
The immunogen is located within the last 50 amino acids of NALP11.
Conjugate:
Unconjugated
Tested Applications:
ELISA, ICC, IF, WB
Application Note:
NALP11 antibody can be used for detection of NALP11 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Positive Control 1:
Cat. No. 1201 - HeLa Cell Lysate
Positive Control 2:
Cat. No. 17-001 - HeLa Cell Slide
Purification:
NALP11 Antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
NALP11 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
NALP11 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
NLRP11
Additional Names:
NALP11 Antibody: NOD17, PAN10, NALP11, PYPAF6, PYPAF7, CLR19.6, NOD17, NACHT, LRR and PYD domains-containing protein 11, Nucleotide-binding oligomerization domain protein 17
Protein Accession Number:
NP_659444
Protein Gi Number:
194018484
Ncbi Gene Id Number:
204801
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
NALP11 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP11 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP11, it has been suggested that it has been associated with Crohn's disease.
Background Reference 1:
Tschopp J, Martinon F, and Burns K. NALPs: a novel protein family involved in inflammation. Nat. Rev. Mol. Cell Biol.2003; 4:95-104.
Background Reference 2:
Tian X, Pascal G, and Monget P. Evolution and functional divergence of NLRP genes in mammalian reproductive system. BMC Evol. Biol.2009; 9:202.
Background Reference 3:
Cummings JR, Cooney RM, Clarke G, et al. The genetics of NOD-like receptors in Crohn's disease. Tiss. Antigens2010; 76:48-56.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

5969

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

Datasheet
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