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NALP3 Antibody [Nalpy3-b]

CATALOG NUMBER: XA-1033

Clonality:
Monoclonal
Tested Applications:
IP, WB
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Immunogen:
NALP3 (monoclonal Nalpy3-b) antibody was raised against recombinant human NALP3.
Conjugate:
Unconjugated
Tested Applications:
IP, WB
Application Note:
NALP3 antibody can be used to recognize human NALP3. It detects endogenous protein by Immunoprecipitation (1:50) and Western Blot (1:1,000). This product is for research use only.
Purification:
NALP3 (monoclonal Nalpy3-b) antibody was purified from concentrated hybridoma tissue culture supernatant. NALP3 (monoclonal Nalpy3-b) antibody was purified to ≥95% in SDS-PAGE.
Clonality:
Monoclonal
Isotype:
IgG1
Physical State:
Liquid
Buffer:
PBS containing 0.02% sodium azide
Concentration:
batch dependent
Storage Conditions:
NALP3 antibody can be stored at 4°C, stable for one year.
Ncbi Gene Id Number:
114548
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background Reference 1:
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder: L. Agostini, et al.; Immunity 20, 319 (2004).
Background Reference 2:
Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation: M. Chamaillard, et al.; Cell. Microbiol. 5, 581 (2003).
Background Reference 3:
Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties: W. O'Connor, Jr., et al.; J. Immunol. 171, 6329 (2003).
Background Reference 4:
Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases: F. Martinon and J. Tschopp; Cell 117, 561 (2004).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

XA-1033

List Size:
0.1 mg

List Price:

$515.00

Datasheet
Shipping Info

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