NDST3 Antibody

CATALOG NUMBER: 59-371

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This NDST3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 809-836 amino acids from the C-terminal region of human NDST3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
101 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
NDST3
Additional Names:
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3, Glucosaminyl N-deacetylase/N-sulfotransferase 3, NDST-3, hNDST-3, N-heparan sulfate sulfotransferase 3, N-HSST 3, Heparan sulfate N-deacetylase 3, 3---, Heparan sulfate N-sulfotransferase 3, 282-, NDST3, HSST3
Protein Accession Number:
O95803
Ncbi Gene Id Number:
9348
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the heparan sulfate/heparinGlcNAc N-deacetylase/ N-sulfotransferase family. The encoded enzymeis a type II transmembrane protein that resides in the Golgiapparatus. This monomeric bifunctional enzyme catalyzes theN-deacetylation and N-sulfation of N-acetylglucosamine residues inheparan sulfate and heparin, which are the initial chemicalmodifications required for the biosynthesis of the functionaloligosaccharide sequences that define the specific ligand bindingactivities of heparan sulfate and heparin.
Background Reference 1:
Feng, T., et al. Hum. Genet. 128(3):269-280(2010)
Background Reference 2:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 3:
Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)
Background Reference 4:
Krenn, E.C., et al. Biochem. Biophys. Res. Commun. 375(3):297-302(2008)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-371

List Size:
400 ul

List Price:

$495.00

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