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Western blot analysis in HepG2 cell line lysates (35ug/lane).
Western blot analysis in HepG2 cell line lysates (35ug/lane).

NEIL2 Antibody

CATALOG NUMBER: 58-223

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This NEIL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the N-terminal region of human NEIL2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
37 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
NEIL2
Additional Names:
Endonuclease 8-like 2, 322-, DNA glycosylase/AP lyase Neil2, DNA-(apurinic or apyrimidinic site) lyase Neil2, Endonuclease VIII-like 2, Nei homolog 2, NEH2, Nei-like protein 2, NEIL2
Protein Accession Number:
Q969S2
Protein Gi Number:
56404653
Ncbi Gene Id Number:
252969
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
NEIL2 belongs to a class of DNA glycosylases homologous tothe bacterial Fpg/Nei family. These glycosylases initiate the firststep in base excision repair by cleaving bases damaged by reactiveoxygen species and introducing a DNA strand break via theassociated lyase reaction (Bandaru et al., 2002 [PubMed12509226])
Background Reference 1:
Briggs, F.B., et al. Am. J. Epidemiol. 172(2):217-224(2010)
Background Reference 2:
Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press :
Background Reference 3:
Grin, I.R., et al. Biochem. Biophys. Res. Commun. 394(1):100-105(2010)
Background Reference 4:
Kinslow, C.J., et al. Genes Chromosomes Cancer 47(11):923-932(2008)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-223

List Size:
400 ul

List Price:

$495.00

Datasheet
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