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Antibody used in IHC on Human Muscle.
Antibody used in WB on Human Fetal Pancreas at 5.0 ug/ml.
Antibody used in IHC on Human Muscle.

NEU1 Antibody

CATALOG NUMBER: 29-977

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NEU1.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, WB
Application Note:
NEU1 antibody can be used for detection of NEU1 by ELISA at 1:312500. NEU1 antibody can be used for detection of NEU1 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Fetal Pancreas Lysate
Predicted Molecular Weight:
40 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store NEU1 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
NEU1
Additional Names:
NEU1, NEU, SIAL1, NANH
Protein Accession Number:
NP_000425
Protein Gi Number:
4557791
Ncbi Gene Id Number:
4758
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
NEU1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A. Mutations in NEU1 gene can lead to sialidosis.The protein encoded by this gene encodes the lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis.
Background Reference 1:
Hinek, A., (2006) J. Biol. Chem. 281 (6), 3698-3710.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

29-977

List Size:
100 ul

List Price:

$473.00

Datasheet
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