Neuritin Recombinant Protein

CATALOG NUMBER: 40-507

Specifications
source-species:
E. coli
Species:
Human
source-species:
E. coli
Recombinant Protein Sequence:
MAGKCDAVFK GFSDCLLKLG DSMANYPQGL DDKTNIKTVC TYWEDFHSCT VTALTDCQEG AKDMWDKLRK ESKNLNIQGS LFELCGSGN
Biological Activity:
Biological activity was determined by a cell proliferation using rat C6 cells. The ED50 for this effect is 20.0 - 30.0 ng/mL.
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized Neuritin recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Neuritin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing Neuritin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
NRN1
Additional Names:
NRN, dJ380B8.2, NRN, Neuritin
Protein Accession Number:
NP_001265639.1
Protein Gi Number:
525314165
Ncbi Gene Id Number:
51299
Background:
Neuritin is a neurotrophic factor, which is expressed in response to induction of neuronal activity by NGF, BDNF, NT3, and other neural stimulators. It is expressed primarily in postmitotic-differentiating neurons of the developing nervous system and in neuronal structures related to synaptic plasticity in the adult nervous system. Neuritin acts as a molecular mediator of neurite outgrowth, neuronal survival, and synaptic maturation. Recombinant human Neuritin is a covalently disulfide-linked homodimer, consisting of two 9.7 kDa polypeptide monomers, each containing 88 amino acid residues.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-507

List Size:
0.005 mg, 0.02 mg

List Price:

Price range: $215.00 through $323.00

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