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Western blot analysis of lysed extracts from HL60 cells using NFκB-p100/p52 (Ab-870).
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using NFκB-p100/p52 (Ab-870).
Western blot analysis of lysed extracts from HL60 cells using NFκB-p100/p52 (Ab-870).

NFkB p100 / p52 (Ab 870) Antibody

CATALOG NUMBER: 79-266

Clonality:
Polyclonal
Tested Applications:
IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
NFkB-p100/p52 (Ab-870) antibody was raised against a peptide sequence around aa.868~872 (Y-G-S-Q-S) derived from Human NFκB-p100/p52.
Conjugate:
Unconjugated
Tested Applications:
IHC, WB
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Specificity:
This antibody detects endogenous level of total NFκB-p100/p52 protein.
Predicted Molecular Weight:
120 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
NFKB2
Additional Names:
p52, p105, H2TF1, LYT10, CVID10, LYT-10, NF-kB2, FKHR, FOXO1A, DNA-binding factor KBF2, Lymphocyte translocation chromosome 10, Lyt10, NFKB2
Protein Accession Number:
NP_001070961.1
Protein Gi Number:
117320540
Ncbi Gene Id Number:
4791
Background:
NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-κ-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-κ-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.
Background Reference 1:
Qu Z, et al. (2004) J Biol Chem; 279 (43): 44563-72. Xiao G, et al. (2001) J Biol Chem 7 (2): 401-9.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-266

List Size:
0.1 mg

List Price:

$370.00

Datasheet
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