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Western blot analysis of lysed extracts from HT29 cells using NFκB-p100/p52 (Ab-872).
<b>Top Image:</b> Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using NFκB-p100/p52 (Ab-872).<b>Bottom Image:</b> Immunofluorescence staining of methanol-fixed HeLa cells using NFκB-p100/p52 (Ab-872).
Western blot analysis of lysed extracts from HT29 cells using NFκB-p100/p52 (Ab-872).

NFkB p100 / p52 (Ab 872) Antibody

CATALOG NUMBER: 79-405

Clonality:
Polyclonal
Tested Applications:
IF, IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
NFkB-p100/p52 (Ab-872) antibody was raised against a peptide sequence around aa.870~874 (S-Q-S-V-E) derived from Human NFκB-p100/p52.
Conjugate:
Unconjugated
Tested Applications:
IF, IHC, WB
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Specificity:
This antibody detects endogenous level of total NFκB-p100/p52 protein.
Predicted Molecular Weight:
52, 120 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
NFKB2
Additional Names:
p52, p105, H2TF1, LYT10, CVID10, LYT-10, NF-kB2, FLK1, VEGFR2, DNA-binding factor KBF2, Lymphocyte translocation chromosome 10, Lyt10, NFKB2
Protein Accession Number:
NP_001070961.1
Protein Gi Number:
117320540
Ncbi Gene Id Number:
4791
Background:
NF-κ-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-κ-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.
Background Reference 1:
Shin HM, et al. (2006) EMBO J; 25 (1): 129-138. Li Q, et al. (2005) Proc Natl Acad Sci USA; 102 (35): 12425-12430. Chen C, et al. (2000) Mol Cell Biol; 20 (8): 2687-2695.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-405

List Size:
0.1 mg

List Price:

$370.00

Datasheet
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