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NFKB1 Antibody

CATALOG NUMBER: XW-7407

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Immunogen:
432-499
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
NFkB antibody can be used for the detection of NFkB by Western blot, may also work for IHC and ICC.
Predicted Molecular Weight:
105.4 kDa (calculated)
Purification:
Antigen affinity-purified
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Storage Conditions:
NFKB1 antibody can be stored at 4°C for short term (weeks). Long term storage should be at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
NFKB1
Additional Names:
Nuclear factor NF-kappa-B p105 subunit, DNA-binding factor KBF1,
Protein Accession Number:
NP_003989.1
Protein Gi Number:
10835177, 189178
Ncbi Gene Id Number:
4790
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Nuclear factor κ-B DNA binding subunit; Nuclear factor of κ light chain gene enhancer in B-cells 1 (p105). NFκB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFκB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-κ-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-κ-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.
Background Reference 1:
Anest, V., Hanson, J. L., Cogswell, P. C., Steinbrecher, K. A., Strahl, B. D., Baldwin, A. S. A nucleosomal function for I-kappa-B kinase-alpha in NF-kappa-B-dependent gene expression. Nature 423: 659-663, 2003.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

XW-7407

List Size:
0.05 mg

List Price:

$615.00

Out of stock

Datasheet
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