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NGF beta Recombinant Protein

CATALOG NUMBER: 40-505

Specifications
source-species:
E. coli
Species:
Murine
source-species:
E. coli
Recombinant Protein Sequence:
MSSTHPVFHM GEFSVCDSVS VWVGDKTTAT DIKGKEVTVL AEVNINNSVF RQYFFETKCR ASNPVESGCR GIDSKHWNSY CTTTHTFVKA LTTDEKQAAW RFIRIDTACV CVLSRKATRR G
Biological Activity:
The ED50 was determined by the dose - dependent stimulation of the proliferation of human TF - 1 cells is < 1.0 ng/mL, corresponding to a specific activity of 1 x 106 units/mg.
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized NGF beta recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted NGF beta is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing NGF beta recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
Ngf
Additional Names:
Ngfb, Ngfb, Beta-nerve growth factor, Beta-NGF
Protein Accession Number:
NP_001106168.1
Protein Gi Number:
162951831
Ncbi Gene Id Number:
18049
Background:
β-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. β-NGF is a potent neurotrophic factor that signals through its receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. β-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. The functional form of Recombinant Murine β-NGF is a non-covalently-linked homodimer of two 13.4 kDa, polypeptide monomers that each contain 120 amino acids and three disulfide bonds, which are required for biological activity.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-505

List Size:
0.005 mg, 0.02 mg

List Price:

$215.00

Datasheet
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