NHEJ1 Antibody

CATALOG NUMBER: 57-772

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This NHEJ1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 268-296 amino acids from the C-terminal region of human NHEJ1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
33 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
NHEJ1
Additional Names:
Non-homologous end-joining factor 1, Protein cernunnos, XRCC4-like factor, NHEJ1, XLF
Protein Accession Number:
Q9H9Q4
Protein Gi Number:
74734059
Ncbi Gene Id Number:
79840
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Double-strand breaks in DNA result from genotoxic stressesand are among the most damaging of DNA lesions. This gene encodes aDNA repair factor essential for the nonhomologous end-joiningpathway, which preferentially mediates repair of double-strandedbreaks. Mutations in this gene cause different kinds of severecombined immunodeficiency disorders.
Background Reference 1:
Malivert, L., et al. J. Biol. Chem. 285(34):26475-26483(2010)
Background Reference 2:
Briggs, F.B., et al. Am. J. Epidemiol. 172(2):217-224(2010)
Background Reference 3:
Okada, Y., et al. Hum. Mol. Genet. 19(11):2303-2312(2010)
Background Reference 4:
Andres, S.N., et al. Mol. Cell 28(6):1093-1101(2007)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-772

List Size:
400 ul

List Price:

$495.00

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