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NKG2-A/C/E Antibody [20d5] (Biotin)

CATALOG NUMBER: 98-949

Clonality:
Monoclonal
Tested Applications:
Blocking, Cytotoxicity Assay, Flow, IHC-Fr, IHC-P, IP, Separation
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
Biotin
Specifications
Host Species:
Rat
Species Reactivity:
Mouse
Immunogen:
CHO cells transfected with B6 allele of NKG2A gene
Conjugate:
Biotin
Tested Applications:
Blocking, Cytotoxicity Assay, Flow, IHC-Fr, IHC-P, IP, Separation
Application Note:
NKG2-A/C/E Antibody [20d5] for use in flow cytometry assays.
Specificity:
NKG2-A/C/E
Clonality:
Monoclonal
Isotype:
IgG2a
physical-state:
Liquid
Buffer:
Supplied in PBS/NaN3
Concentration:
0.5 mg/mL
Storage Conditions:
Store vial at 2-8°C
Ncbi Official Symbol:
Klrc1
Additional Names:
NKG2A, NKG2C, NKG2E
Ncbi Gene Id Number:
16641;16642;58179
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The monoclonal antibody 20d5 reacts with an epitope common to the NKG2A, NKG2C and NKG2E isoforms of the NKG2 heterodimer, a member of the c-type lectin family of inhibitory receptors. Mouse NKG2 is a natural killer (NK) cell receptor for the non-classical MHC class I molecule Qa-1b. NKG2 is expressed on NK cells, lymphokine-activated killer (LAK) T cells, and some CD8+ memory T cells. Two-color immunofluorescent staining with the 20d5 antibody reveals two distinct NKG2+ phenotypes within the NK1.1+CD3- spleen cell population: NKG2hi (50%) and NKG2low (50%). With the exception of DBA/2J mice, NKG2 is expressed on NK1.1+ cells from all mouse strains tested (C57BL/6, BALB/c, 129/J, C3H.SW, AKR/J, SJL).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

98-949

List Size:
0.5 mg

List Price:

$463.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

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