NKX2-2 Antibody

CATALOG NUMBER: 25-413

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NKX2-2.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
NKX2-2 antibody can be used for detection of NKX2-2 by ELISA at 1:1562500. NKX2-2 antibody can be used for detection of NKX2-2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1309 - Human Placenta Lysate
Predicted Molecular Weight:
30 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store NKX2-2 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
NKX2-2
Additional Names:
NKX2-2, NKX2.2, NKX2B
Protein Accession Number:
NP_002500
Protein Gi Number:
4505401
Ncbi Gene Id Number:
4821
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Nkx2-2 contains 1 homeobox DNA-binding domain which is essential for interaction with OLIG2. Nkx2-2 may be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. The protein encoded by this gene contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. This gene is found on chromosome 20 near NKX2-4, and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor.
Background Reference 1:
Owen, L.A., (er) PLoS ONE 3 (4), E1965 (2008).

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

25-413

List Size:
100 ul

List Price:

$519.00

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