NLN Antibody

CATALOG NUMBER: 60-788

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This NLN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-240 amino acids from the Central region of human NLN.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
81 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
NLN
Additional Names:
Neurolysin, mitochondrial, Angiotensin-binding protein, Microsomal endopeptidase, MEP, Mitochondrial oligopeptidase M, Neurotensin endopeptidase, NLN, AGTBP, KIAA1226
Protein Accession Number:
Q9BYT8
Protein Gi Number:
20139130
Ncbi Gene Id Number:
57486
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the metallopeptidase M3protein family that cleaves neurotensin at the Pro10-Tyr11 bond,leading to the formation of neurotensin(1-10) andneurotensin(11-13). The encoded protein is likely involved in thetermination of the neurotensinergic signal in the central nervoussystem and in the gastrointestinal tract.
Background Reference 1:
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Background Reference 2:
Lim, E.J., et al. J. Biol. Chem. 282(13):9722-9732(2007)
Background Reference 3:
Norman, M.U., et al. Am. J. Physiol. Heart Circ. Physiol. 284 (6), H1978-H1984 (2003) :
Background Reference 4:
Norman, M.U., et al. Am. J. Physiol. Heart Circ. Physiol. 284 (6), H1978-H1984 (2003) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-788

List Size:
400 ul

List Price:

$495.00

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