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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

NMNAT3 Antibody

CATALOG NUMBER: 57-468

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This NMNAT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-178 amino acids from the Central region of human NMNAT3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
28 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
NMNAT3
Additional Names:
Nicotinamide mononucleotide adenylyltransferase 3, NMN adenylyltransferase 3, Nicotinate-nucleotide adenylyltransferase 3, NaMN adenylyltransferase 3, Pyridine nucleotide adenylyltransferase 3, PNAT-3, NMNAT3
Protein Accession Number:
Q96T66
Protein Gi Number:
116242680
Ncbi Gene Id Number:
349565
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The coenzyme NAD and its derivatives are involved inhundreds of metabolic redox reactions and are utilized in proteinADP-ribosylation, histone deacetylation, and in some Ca(2+)signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NADbiosynthesis, catalyzing the condensation of nicotinamidemononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) withthe AMP moiety of ATP to form NAD or NaAD (Zhang et al., 2003[PubMed 12574164]).
Background Reference 1:
Di Stefano, M., et al. Blood Cells Mol. Dis. 45(1):33-39(2010)
Background Reference 2:
Lau, C., et al. J. Biol. Chem. 285(24):18868-18876(2010)
Background Reference 3:
Sorci, L., et al. Biochemistry 46(16):4912-4922(2007)
Background Reference 4:
Berger, F., et al. J. Biol. Chem. 280(43):36334-36341(2005)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-468

List Size:
400 ul

List Price:

$495.00

Datasheet
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