NOXO1 Antibody

CATALOG NUMBER: 59-241

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This NOXO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-219 amino acids from the Central region of human NOXO1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
41 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
NOXO1
Additional Names:
NADPH oxidase organizer 1, NADPH oxidase regulatory protein, Nox organizer 1, Nox-organizing protein 1, SH3 and PX domain-containing protein 5, NOXO1, P41NOX, SH3PXD5
Protein Accession Number:
Q8NFA2
Protein Gi Number:
74751269
Ncbi Gene Id Number:
124056
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
NADPH oxidases (NOXs) catalyze the transfer of electronsfrom NADPH to molecular oxygen to generate reactive oxygen species(ROS). NOX organizers, such as NOXO1, target NOX activators (seeNOXA1; MIM 611255) to NOX and also target NOX to differentsubcellular compartments (Opitz et al., 2007 [PubMed17189823]).
Background Reference 1:
Dutta, S., et al. PLoS ONE(5), E10478 (2010) :
Background Reference 2:
Opitz, N., et al. Free Radic. Biol. Med. 42(2):175-179(2007)
Background Reference 3:
Yamamoto, A., et al. Biochem. Biophys. Res. Commun. 352(2):560-565(2007)
Background Reference 4:
Takeya, R., et al. FEBS J. 273(16):3663-3677(2006)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-241

List Size:
400 ul

List Price:

$495.00

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