NPW Antibody

CATALOG NUMBER: 64-046

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This NPW antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-150 amino acids from the C-terminal region of human NPW.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
18 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
NPW
Additional Names:
Neuropeptide W, Preproprotein L8, hPPL8, Neuropeptide W-23, NPW23, hL8, Neuropeptide W-30, NPW30, hL8C, NPW, PPL8, PPNPW
Protein Accession Number:
Q8N729
Ncbi Gene Id Number:
283869
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
NPW is processed into 23- and 30-amino acid neuropeptides that bind and activate two G-protein coupled receptors in the central nervous system. The neuropeptides have been shown to enhance cortisol secretion from adrenal cells through the adenylate cyclase/protein kinase A signaling cascade. The preproprotein is translated using a non-AUG initiation codon that is inferred from analyses of the mouse ortholog. [provided by RefSeq].
Background Reference 1:
Luttrell, L.M. Mol. Biotechnol. 39(3):239-264(2008)
Background Reference 2:
Singh, G., et al. Br. J. Pharmacol. 148(8):1033-1041(2006)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

64-046

List Size:
400 ul

List Price:

$495.00

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