NPY1R Antibody

CATALOG NUMBER: 60-137

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Pig
Immunogen:
This NPY1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-260 amino acids from the Central region of human NPY1R.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
44 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
NPY1R
Additional Names:
Neuropeptide Y receptor type 1, NPY1-R, NPY1R, NPYR, NPYY1
Protein Accession Number:
P25929
Protein Gi Number:
128997
Ncbi Gene Id Number:
4886
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Neuropeptide Y (NPY; MIM 162640) is one of the mostabundant neuropeptides in the mammalian nervous system and exhibitsa diverse range of important physiologic activities, includingeffects on psychomotor activity, food intake, regulation of centralendocrine secretion, and potent vasoactive effects on thecardiovascular system. Two major subtypes of NPY (Y1 and Y2) havebeen defined by pharmacologic criteria. NPY receptors, such asNPY1R, have been identified in a variety of tissues, includingbrain, spleen, small intestine, kidney, testis, placenta, andaortic smooth muscle (Herzog et al., 1992 [PubMed1321422]).
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Kim, H.Y., et al. BMB Rep 43(8):547-553(2010)
Background Reference 3:
Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Background Reference 4:
Naukkarinen, J., et al. PLoS Genet.(6), E1000976 (2010) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-137

List Size:
400 ul

List Price:

$495.00

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