NQO1 Antibody

CATALOG NUMBER: 33-029

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
A recombinant protein fragment from the C-terminal region of human NQO1 was used as the immunogen for this antibody.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western blot: 1-3 ug/ml
Provided assay concentrations are suggestions only, NQO1 antibody titration may be required for optimal results.
Purification:
Protein A affinity chromatography
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.5 mg/mL
Storage Conditions:
Aliquot and Store at -20°C. Avoid freez-thaw cycles.
Ncbi Official Symbol:
NQO1
Additional Names:
NAD(P)H dehydrogenase [quinone] 1, Azoreductase, DT-diaphorase, DTD, Menadione reductase, NAD(P)H:quinone oxidoreductase 1, Phylloquinone reductase, Quinone reductase 1, QR1, NQO1, DIA4, NMOR1
Ncbi Gene Id Number:
1728
User Note:
Optimal dilutions for each application to be determined by the researcher
Background:
NAD(P)H:quinone oxidoreductase is an enzyme that catalyzes the two-electron reduction of quinones to hydroquinones, resulting in the activation or deactivation of the hydroquinone. Increased expression of NQO1 is seen in tumors of the breast, liver and colon and NSCLC or ‘non-small cell lung cancer,’ suggesting a role in tumor development and possibly treatment. NQO1 has also been linked to Alzheimer's disease, found to be upregulated in response to the oxidative stress of the AD process.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

33-029

List Size:
100 ug

List Price:

$520.00

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