NR1D2 Antibody

CATALOG NUMBER: 28-893

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR1D2.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
NR1D2 antibody can be used for detection of NR1D2 by ELISA at 1:62500. NR1D2 antibody can be used for detection of NR1D2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1205 - Jurkat Cell Lysate
Predicted Molecular Weight:
65 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store NR1D2 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
NR1D2
Additional Names:
NR1D2, RVR, BD73, EAR-1R
Protein Accession Number:
NP_005117
Protein Gi Number:
224177491
Ncbi Gene Id Number:
9975
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
NR1D2 can interact with NCOA5 coactivator, leading to a strong increase of transcription of target genes. NR1D2 also binds to the sequences 5'-AATGTAGGTCA-3' and 5'-ATAACTAGGTCA-3' and acts as a potent competitive transcriptional silencer and negative regulator of RORalpha mediated trans-activation. NR1D2 may play different roles in metabolism, inflammation, and circadian cycling in the organ-specific manner in homeostasis.
Background Reference 1:
Sauve, F., et al., (2001) Mol. Cell. Biol. 21 (1), 343-353.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

28-893

List Size:
100 ul

List Price:

$473.00

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