NR1I3 Antibody

CATALOG NUMBER: 27-919

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR1I3.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
NR1I3 antibody can be used for detection of NR1I3 by ELISA at 1:62500. NR1I3 antibody can be used for detection of NR1I3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1211 - HepG2 Cell Lysate
Predicted Molecular Weight:
40 kDa, 38 kDa, 32 kDa, 35 kDa, 37 kDa, 36 kDa, 33 kDa, 30 kDa, 35 kDa, 35 kDa, 38 kDa, 36 kDa, 40 kDa, 36 kDa, 40 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store NR1I3 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
NR1I3
Additional Names:
NR1I3, CAR, CAR-BETA, CAR-SV1, CAR-SV10, CAR-SV11, CAR-SV12, CAR-SV13, CAR-SV14, CAR-SV15, CAR-SV17, CAR-SV18, CAR-SV19, CAR-SV20, CAR-SV21, CAR-SV4, CAR-SV6, CAR-SV7, CAR-SV8, CAR-SV9, CAR1, MB67, MGC97144
Protein Accession Number:
NP_005113
Protein Gi Number:
4826661
Ncbi Gene Id Number:
9970
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
NR1I3 is a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members.
Background Reference 1:
Ferguson, S.S., (2005) Mol. Pharmacol. 68 (3), 747-757.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

27-919

List Size:
100 ul

List Price:

$473.00

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