NR1I3 Antibody

CATALOG NUMBER: 28-750

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of mouse NR1I3.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
NR1I3 antibody can be used for detection of NR1I3 by ELISA at 1:312500. NR1I3 antibody can be used for detection of NR1I3 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1282 - 3T3 (NIH) Cell Lysate
Predicted Molecular Weight:
39 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store NR1I3 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
NR1I3
Additional Names:
NR1I3, CAR, MB67, Care2, ESTM32, AA209988, AI551208, CAR-beta
Protein Accession Number:
NP_033933
Protein Gi Number:
83921568
Ncbi Gene Id Number:
12355
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
NR1I3 mediates the induction of transcription of cytochrome P450 (CYP) genes by phenobarbital (PB) and PB-type inducers. NR1I3 activation induces hepatic expression of detoxification enzymes and transporters and increases liver size. NR1I3 can also regulate both liver homeostasis and tumorigenesis in response to xenobiotic stresses.
Background Reference 1:
Briancon, N. (2006) EMBO J. 25 (6), 1253-1262.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

28-750

List Size:
100 ul

List Price:

$473.00

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