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Antibody used in WB on Human HCT15 at 2.5 ug/ml.
Antibody used in WB on Human HCT15 at 2.5 ug/ml.

NR2C1 Antibody

CATALOG NUMBER: 31-191

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Dog, Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Dog, Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR2C1.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
NR2C1 antibody can be used for detection of NR2C1 by ELISA at 1:312500. NR2C1 antibody can be used for detection of NR2C1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
HCT15 Cell Lysate
Predicted Molecular Weight:
67 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store NR2C1 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
NR2C1
Additional Names:
NR2C1, TR2
Protein Accession Number:
NP_003288
Protein Gi Number:
189491739
Ncbi Gene Id Number:
7181
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The nuclear orphan receptors NR2C1 represses transcription and binds DNA as a homodimer. NR2C1 binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. NR2C1 may function as a negative modulator to suppress androgen receptor function in prostate cancer. NR2C1 may exert an important repressor in regulating ER activity in mammary glands. The nuclear orphan receptors TR2 (NR2C1) and TR4 form a heterodimer that binds to the epsilon and gamma globin promoter DR1 sites
Background Reference 1:
Li, G., et al., (2003) Biochem. Biophys. Res. Commun. 310 (2), 384-390.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

31-191

List Size:
100 ul

List Price:

$473.00

Datasheet
Shipping Info

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