NR2C1 Antibody

CATALOG NUMBER: 58-293

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Monkey
Immunogen:
This NR2C1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 516-545 amino acids from the C-terminal region of human NR2C1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
67 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
NR2C1
Additional Names:
Nuclear receptor subfamily 2 group C member 1, Orphan nuclear receptor TR2, Testicular receptor 2, NR2C1, TR2
Protein Accession Number:
P13056
Protein Gi Number:
226693548
Ncbi Gene Id Number:
7181
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a nuclear hormone receptor characterizedby a highly conserved DNA binding domain (DBD), a variable hingeregion, and a carboxy-terminal ligand binding domain (LBD) that istypical for all members of the steroid/thyroid hormone receptorsuperfamily. This protein also belongs to a large family ofligand-inducible transcription factors that regulate geneexpression by binding to specific DNA sequences within promoters oftarget genes. Multiple alternatively spliced transcript variantshave been described, but the full-length nature of some of thesevariants has not been determined.
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Lin, Y.L., et al. Biochem. Biophys. Res. Commun. 350(2):430-436(2006)
Background Reference 3:
Li, G., et al. Biochem. Biophys. Res. Commun. 310(2):384-390(2003)
Background Reference 4:
Mu, X., et al. Prostate 57(2):129-133(2003)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-293

List Size:
400 ul

List Price:

$495.00

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