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Antibody used in IHC on Human kidney.
Antibody used in WB on Human A172 at 1.25 ug/ml.
Antibody used in IHC on Human kidney.

NR3C2 Antibody

CATALOG NUMBER: 30-075

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR3C2.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, WB
Application Note:
NR3C2 antibody can be used for detection of NR3C2 by ELISA at 1:312500. NR3C2 antibody can be used for detection of NR3C2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
A172 Cell Lysate
Predicted Molecular Weight:
107 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store NR3C2 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
NR3C2
Additional Names:
NR3C2, MCR, MGC133092, MLR, MR, NR3C2VIT
Protein Accession Number:
NP_000892
Protein Gi Number:
158508572
Ncbi Gene Id Number:
4306
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
NR3C2 is a receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. It binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
Background Reference 1:
Liu, G., (2006) Biochem. Biophys. Res. Commun. 342 (4), 1291-1296.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

30-075

List Size:
100 ul

List Price:

$473.00

Datasheet
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