NS Antibody

CATALOG NUMBER: XW-7166

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Immunogen:
1-280
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
E2IG3 antibody can be used for the detection of E2IG3 by Western blot, may also work for IHC and ICC.
Predicted Molecular Weight:
62 kDa (calculated)
Purification:
Antigen affinity-purified
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Storage Conditions:
NS antibody can be stored at 4°C for short term (weeks). Long term storage should be at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GNL3
Additional Names:
E2IG3, NS, Guanine nucleotide-binding protein-like 3, E2-induced gene 3 protein, NNP47, E2IG3, C77032
Protein Accession Number:
NP_055181.2
Protein Gi Number:
7657048
Ncbi Gene Id Number:
26354
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Nucleostemin; putative nucleotide binding protein, estradiol-induced; E2IG3. This protein may play a role in maintaining stem cell self-renewal. Depletion or overexpression of nucleostemin reduces cell proliferation in CNS stem cells and transformed cells. Mutation analysis indicated that excessive nucleostemin, particularly mutants lacking the GTP-regulatory domain, prevents cells from entering mitosis and causes apoptosis in a p53-dependent manner. The N-terminal basic domain mediates the interaction with p53 and is required for the cell death caused by overexpression.
Background Reference 1:
Tsai, R. Y. L., McKay, R. D. G. A nucleolar mechanism controlling cell proliferation in stem cells and cancer cells. Genes Dev. 16: 2991-3003, 2002.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

XW-7166

List Size:
0.05 mg

List Price:

$565.00

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