NT-3 Recombinant Protein

CATALOG NUMBER: 40-497

Specifications
source-species:
E. coli
Species:
Human
source-species:
E. coli
Recombinant Protein Sequence:
MYAEHKSHRG EYSVCDSESL WVTDKSSAID IRGHQVTVLG EIKTGNSPVK QYFYETRCKE ARPVKNGCRG IDDKHWNSQC KTSQTYVRAL TSENNKLVGW RWIRIDTSCV CALSRKIGRT
Biological Activity:
Determined by its ability to bind recombinnat human TrkBeta Fc Chimera in functional ELISA.
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized NT-3 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted NT-3 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing NT-3 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
NTF3
Additional Names:
NT3, HDNF, NGF2, NT-3, NGF-2, Neurotrophin-3
Protein Accession Number:
NP_001096124.1
Protein Gi Number:
156630995
Ncbi Gene Id Number:
4908
Background:
NT-3 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant human NT-3 is a noncovalently linked homodimer, of two 13.6 kDa polypeptide monomers (240 total amino acid residues). Human and Mouse NT-3 sequences are identical.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-497

List Size:
0.002 mg, 0.01 mg

List Price:

Price range: $215.00 through $323.00

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