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NT-4 Recombinant Protein

CATALOG NUMBER: 40-566

Specifications
source-species:
E. coli
Species:
Human
source-species:
E. coli
Recombinant Protein Sequence:
GVSETAPASR RGELAVCDAV SGWVTDRRTA VDLRGREVEV LGEVPAAGGS PLRQYFFETR CKADNAEEGG PGAGGGGCRG VDRRHWVSEC KAKQSYVRAL TADAQGRVGW RWIRIDTACV CTLLSRTGRA
Biological Activity:
The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found in the range of 20-50 ng/mL. Endotoxin level is less than 0.1 ng per μg of NT-4 (1EU/μg).
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
physical-state:
Lyophilized
Storage Conditions:
The lyophilized NT-4 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted NT-4 stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing NT-4 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
NTF4
Additional Names:
NT4, NT5, NT-4, NT-5, NTF5, GLC10, GLC1O, NT-4/5, Neurotrophin-4, Neurotrophin-5
Protein Accession Number:
NP_006170.1
Protein Gi Number:
5453808
Ncbi Gene Id Number:
4909
Background:
NT-4 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues).Manufactured using all non-animal reagents.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-566

List Size:
0.01 mg

List Price:

$370.00

Datasheet
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