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Nuclear Receptor NR4A1 (phospho Ser351) Antibody

CATALOG NUMBER: 79-822

Clonality:
Polyclonal
Tested Applications:
IHC
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Nuclear Receptor NR4A1 (phospho Ser351) antibody was raised against a peptide sequence around phosphorylation site of Serine351 (L-P-S (p)-K-P) derived from Human Nuclear Receptor NR4A1.
Conjugate:
Unconjugated
Tested Applications:
IHC
Specificity:
The antibody detects endogenous levels of Nuclear Receptor NR4A1 only when phosphorylated at serine 351
Predicted Molecular Weight:
64 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
NR4A1
Additional Names:
NGFIB, GFRP1, HMR, NR4A1, NAK1
Protein Accession Number:
NP_002126.2
Protein Gi Number:
27894346
Ncbi Gene Id Number:
3164
Background:
Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation.
Background Reference 1:
Nakai A., Mol. Endocrinol. 4:1438-1443(1990).
Background Reference 2:
Chang C., J. Steroid Biochem. 34:391-395(1989).
Background Reference 3:
Bondy G.P., Cell Growth Differ. 2:203-208(1991)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-822

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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