NUP88 Antibody

CATALOG NUMBER: 57-528

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This NUP88 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 701-730 amino acids from the C-terminal region of human NUP88.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
84 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
NUP88
Additional Names:
Nuclear pore complex protein Nup88, 88 kDa nucleoporin, Nucleoporin Nup88, NUP88
Protein Accession Number:
Q99567
Protein Gi Number:
25008854
Ncbi Gene Id Number:
4927
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The nuclear pore complex is a massive structure thatextends across the nuclear envelope, forming a gateway thatregulates the flow of macromolecules between the nucleus and thecytoplasm. Nucleoporins, a family of 50 to 100 proteins, are themain components of the nuclear pore complex in eukaryotic cells.The protein encoded by this gene belongs to the nucleoporin familyand is associated with the oncogenic nucleoporin CAN/Nup214 in adynamic subcomplex. This protein is also overexpressed in a largenumber of malignant neoplasms and precancerous dysplasias.
Background Reference 1:
Hashizume, C., et al. Mol. Cancer 9, 119 (2010) :
Background Reference 2:
Brustmann, H., et al. Ann Diagn Pathol 13(5):303-307(2009)
Background Reference 3:
Cheng, Y.T., et al. Plant Cell 21(8):2503-2516(2009)
Background Reference 4:
Andres-Hernando, A., et al. J. Biol. Chem. 283(36):25082-25090(2008)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-528

List Size:
400 ul

List Price:

$495.00

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