NXT1 Antibody

CATALOG NUMBER: 60-697

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This NXT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-111 amino acids from the C-terminal region of human NXT1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
16 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
NXT1
Additional Names:
NTF2-related export protein 1, Protein p15, NXT1
Protein Accession Number:
Q9UKK6
Protein Gi Number:
18203504
Ncbi Gene Id Number:
29107
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is located in the nuclearenvelope. It has protein similarity to nuclear transport factor 2.This protein functions as a nuclear export factor in both RAN(Ras-related nuclear protein)- and CRM1 (required for chromosomeregion maintenance)-dependent pathways. It is found to stimulatethe export of U1 snRNA in RAN- and CRM1-dependent pathways and theexport of tRNA and mRNA in a CRM1-independent pathway. The encodedprotein heterodimerizes with Tap protein and may regulate theability of Tap protein to mediate nuclear mRNA export. The use ofalternate polyadenylation sites has been found for this gene.
Background Reference 1:
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
Background Reference 2:
Forler, D., et al. Nat. Biotechnol. 21(1):89-92(2003)
Background Reference 3:
Katahira, J., et al. J. Biol. Chem. 277(11):9242-9246(2002)
Background Reference 4:
Wiegand, H.L., et al. Mol. Cell. Biol. 22(1):245-256(2002)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-697

List Size:
400 ul

List Price:

$495.00

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