Oct-1 Antibody

CATALOG NUMBER: 79-773

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Oct-1 antibody was raised against a peptide sequence around aa.270~274 (T-P-K-R-I) derived from Human Oct-1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
This antibody detects endogenous level of total Oct-1protein.
Predicted Molecular Weight:
90 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
POU2F1
Additional Names:
OCT1, OTF1, oct-1B, 41183
Protein Accession Number:
NP_001185712.1
Protein Gi Number:
311771667
Ncbi Gene Id Number:
5451
Background:
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR By similarity. In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.
Background Reference 1:
Prefontaine G. G., Walther R., Giffin W., Lemieux M. E., Pope L., Hache R. J. G. J. Biol. Chem, 274:26713-26719 (1999) Mahajan S. S., Wilson A. C. Mol. Cell. Biol. 20:919-928 (2000)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-773

List Size:
0.1 mg

List Price:

$370.00

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