ONECUT2 Antibody

CATALOG NUMBER: 25-383

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ONECUT2.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
ONECUT2 antibody can be used for detection of ONECUT2 by ELISA at 1:1562500. ONECUT2 antibody can be used for detection of ONECUT2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
721_B Cell Lysate
Predicted Molecular Weight:
54 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store ONECUT2 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
ONECUT2
Additional Names:
ONECUT2, MGC120377, MGC120378, OC-2, OC2
Protein Accession Number:
NP_004843
Protein Gi Number:
119220564
Ncbi Gene Id Number:
9480
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
ONECUT2 is a member of the transcription factors of the ONECUT class, whose prototype is hepatocyte nuclear factor (HNF)-6. The distribution of OC-2 mRNA in humans is tissue-restricted, the strongest expression being detected in the liver and skin. ONECUT2 participates in the network of transcription factors required for liver differentiation and metabolism. This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation.
Background Reference 1:
Rauch, T., (2006) Cancer Res. 66 (16), 7939-7947.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

25-383

List Size:
100 ul

List Price:

$519.00

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