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Western blot analysis in 293 cell line lysates (35ug/lane).
Western blot analysis in 293 cell line lysates (35ug/lane).

OPCML Antibody

CATALOG NUMBER: 60-633

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Rat
Immunogen:
This OPCML antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-200 amino acids from the Central region of human OPCML.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
38 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
OPCML
Additional Names:
Opioid-binding protein/cell adhesion molecule, OBCAM, OPCML, Opioid-binding cell adhesion molecule, IgLON family member 1, OPCML, IGLON1, OBCAM
Protein Accession Number:
Q14982
Protein Gi Number:
2497326
Ncbi Gene Id Number:
4978
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the IgLON subfamily in theimmunoglobulin protein superfamily. The encoded protein islocalized in the plasma membrane and may have an accessory role inopioid receptor function. This gene has an ortholog in rat andbovine. The opioid binding-cell adhesion molecule encoded by therat gene binds opioid alkaloids in the presence of acidic lipids,exhibits selectivity for mu ligands and acts as a GPI-anchoredprotein. Since the encoded protein is highly conserved in speciesduring evolution, it may have a fundamental role in mammaliansystems. Two transcript variants encoding different isoforms havebeen found for this gene.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care (2010) In press :
Background Reference 2:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 3:
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Background Reference 4:
Stolk, L., et al. Nat. Genet. (2009) In press :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-633

List Size:
400 ul

List Price:

$495.00

Datasheet
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