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Western blot analysis in SH-SY5Y cell line lysates (35ug/lane).
ORC3L Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human lung adenocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in SH-SY5Y cell line lysates (35ug/lane).

ORC3L Antibody

CATALOG NUMBER: 58-059

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This ORC3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human ORC3L.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
82 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ORC3
Additional Names:
Origin recognition complex subunit 3, Origin recognition complex subunit Latheo, ORC3, LATHEO, ORC3L
Protein Accession Number:
Q9UBD5
Protein Gi Number:
8928268
Ncbi Gene Id Number:
23595
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The origin recognition complex (ORC) is a highly conservedsix subunits protein complex essential for the initiation of theDNA replication in eukaryotic cells. Studies in yeast demonstratedthat ORC binds specifically to origins of replication and serves asa platform for the assembly of additional initiation factors suchas Cdc6 and Mcm proteins. The protein encoded by this gene is asubunit of the ORC complex. Studies of a similar gene in Drosophilasuggested a possible role of this protein in neuronal proliferationand olfactory memory. Alternatively spliced transcript variantsencoding distinct isoforms have been reported for this gene.
Background Reference 1:
Enjuanes, A., et al. Cancer Res. 68(24):10178-10186(2008)
Background Reference 2:
DeRosse, P., et al. Schizophr Bull 34(6):1047-1053(2008)
Background Reference 3:
Siddiqui, K., et al. J. Biol. Chem. 282(44):32370-32383(2007)
Background Reference 4:
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-059

List Size:
400 ul

List Price:

$495.00

Datasheet
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