ORL1 / LOX1 / LOXIN Antibody

CATALOG NUMBER: 43-707

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Goat
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Goat
Species Reactivity:
Human
Immunogen:
The immunogen for this antibody is: DLKIQTVKDQPDEK-C
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Approx 40kDa band observed in Human Liver lysates (calculated MW of 30.9kDa according to NP_002534.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Yoshida et al, Biochem J. 1998 Aug 15;334 (Pt 1):9-13. PMID: 9693095). Recommended concentration: 0.1-0.3ug/ml.
Specificity:
This antibody is expected to recognize all reported isoforms (NP_002534.1; NP_001166103.1; NP_001166104.1).
Predicted Molecular Weight:
Approx 40kDa
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.Aliquot and store at -20°C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Storage Conditions:
Aliquot and store at -20°C. Minimize freezing and thawing.
Ncbi Official Symbol:
ORL1 / LOX1 / LOXIN
Additional Names:
OLR1, oxidized low density lipoprotein (lectin-like) receptor 1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1, C-type lectin domain family 8 member A, OTTHUMP00000238950, OTTHUMP00000238954, OTTHUMP00000238955, OTTHUMP00000238958, hLOX-1, lectin-type oxidized LDL r
Protein Accession Number:
NP_002534.1,NP_001166103.1,NP_001166104.1
Protein Gi Number:
119616564
Ncbi Gene Id Number:
4973
Background Reference 1:
Shi Y, Cosentino F, Camici GG, Akhmedov A, Vanhoutte PM, Tanner FC, Lüscher TF.Oxidized low-density lipoprotein activates p66Shc via lectin-like oxidized low-density lipoprotein receptor-1, protein kinase C-beta, and c-Jun N-terminal kinase kinase in human endothelial cells.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

43-707

List Size:
0.1 mg

List Price:

$495.00

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