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Antibody used in WB on Human HT1080 at 0.2-1 ug/ml.
Antibody used in WB on Human HT1080 at 0.2-1 ug/ml.

OSMR Antibody

CATALOG NUMBER: 30-198

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human OSMR.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
OSMR antibody can be used for detection of OSMR by ELISA at 1:12500. OSMR antibody can be used for detection of OSMR by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
HT1080 Cell Lysate
Predicted Molecular Weight:
110 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store OSMR antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
OSMR
Additional Names:
OSMR, MGC150626, MGC150627, MGC75127, OSMRB, PLCA1
Protein Accession Number:
NP_003990
Protein Gi Number:
4557040
Ncbi Gene Id Number:
9180
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF.Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Background Reference 1:
Arita, K., (2008) Am. J. Hum. Genet. 82 (1), 73-80.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

30-198

List Size:
100 ul

List Price:

$519.00

Datasheet
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