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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

OSTM1 Antibody

CATALOG NUMBER: 59-814

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This OSTM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-321 amino acids from the C-terminal region of human OSTM1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
37 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
OSTM1
Additional Names:
Osteopetrosis-associated transmembrane protein 1, Chloride channel 7 beta subunit, OSTM1, GL
Protein Accession Number:
Q86WC4
Protein Gi Number:
51316434
Ncbi Gene Id Number:
28962
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a protein that may be involved in thedegradation of G proteins via the ubiquitin-dependent proteasomepathway. The encoded protein binds to members of subfamily A of theregulator of the G-protein signaling (RGS) family through anN-terminal leucine-rich region. This protein also has a centralRING finger-like domain and E3 ubiquitin ligase activity. Thisprotein is highly conserved from flies to humans. Defects in thisgene may cause the autosomal recessive, infantile malignant form ofosteopetrosis.
Background Reference 1:
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Background Reference 2:
Mazzolari, E., et al. Am. J. Hematol. 84(8):473-479(2009)
Background Reference 3:
Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008)
Background Reference 4:
Feigin, M.E., et al. Cell. Signal. 20(5):949-957(2008)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-814

List Size:
400 ul

List Price:

$495.00

Datasheet
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