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Western blot testing of human samples with OTUD5 antibody at 2ug/ml.
Western blot testing of mouse samples with OTUD5 antibody at 4ug/ml.
Western blot testing of human samples with OTUD5 antibody at 2ug/ml.

OTUD5 Antibody

CATALOG NUMBER: 33-033

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
A recombinant protein fragment from the C-terminal region of human OTUD5 was used as the immunogen for this antibody.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western blot: 2-5 ug/ml
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
Purification:
Protein A affinity chromatography
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.5 mg/mL
Storage Conditions:
Aliquot and Store at -20°C. Avoid freez-thaw cycles.
Ncbi Official Symbol:
OTUD5
Additional Names:
OTUD5 Antibody: DUBA, OTU domain-containing protein 5, Deubiquitinating enzyme A, DUBA
Ncbi Gene Id Number:
55593
User Note:
Optimal dilutions for each application to be determined by the researcher
Background:
OTUD5 (ovarian tumor domain-containing 5), also called DUBA (Deubiquitinating enzyme A), is a product of the OTUD5 gene, and a suppressor of the innate immune response via its deubiquitinating activity. The Innate immune systems provide immediate but short-lived defense against infection identified by PRRs, or pattern recognition receptors. OTUD5 cleaves the lysine-63-linked polyubiquitin chains of TRAF3, causing it to dissociate from TBK1, thereby failing to stimulate IFN type 1 production and leading to a suppressed innate immune response.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

33-033

List Size:
100 ug

List Price:

$520.00

Datasheet
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