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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

P2RX3 Antibody

CATALOG NUMBER: 60-165

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This P2RX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 330-356 amino acids from the C-terminal region of human P2RX3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
44 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
P2RX3
Additional Names:
P2X purinoceptor 3, P2X3, ATP receptor, Purinergic receptor, P2RX3
Protein Accession Number:
P56373
Protein Gi Number:
259016295
Ncbi Gene Id Number:
5024
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The product of this gene belongs to the family ofpurinoceptors for ATP. This receptor functions as a ligand-gatedion channel and may transduce ATP-evoked nociceptor activation.Mouse studies suggest that this receptor is important forperipheral pain responses, and also participates in pathwayscontrolling urinary bladder volume reflexes. It is possible thatthe development of selective antagonists for this receptor may havea therapeutic potential in pain relief and in the treatment ofdisorders of urine storage.
Background Reference 1:
Allsopp, R.C., et al. J. Biol. Chem. 285(43):32770-32777(2010)
Background Reference 2:
Beneng, K., et al. IntOral Maxillofac Surg 39(8):815-819(2010)
Background Reference 3:
Nair, A., et al. Cell. Mol. Neurobiol. 30(4):505-509(2010)
Background Reference 4:
Jacques-Silva, M.C., et al. Proc. Natl. Acad. Sci. U.S.A. 107(14):6465-6470(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-165

List Size:
400 ul

List Price:

$495.00

Datasheet
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