P2RX6 Antibody

CATALOG NUMBER: 58-955

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This P2RX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the Central region of human P2RX6.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
49 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
P2RX6
Additional Names:
P2X purinoceptor 6, P2X6, ATP receptor, P2XM, Purinergic receptor, Purinergic receptor P2X-like 1, P2RX6, P2RXL1, P2X6
Protein Accession Number:
O15547
Ncbi Gene Id Number:
9127
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene belongs to the family ofP2X receptors, which are ATP-gated ion channels and mediate rapidand selective permeability to cations. This gene is predominantlyexpressed in skeletal muscle, and regulated by p53. The encodedprotein is associated with VE-cadherin at the adherens junctions ofhuman umbilical vein endothelial cells. Alternative splicingresults in multiple transcript variants. A related pseudogene,which is also located on chromosome 22, has been identified.
Background Reference 1:
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Background Reference 2:
Luke, M.M., et al. Stroke 40(2):363-368(2009)
Background Reference 3:
Palomino-Doza, J., et al. Hypertension 52(5):980-985(2008)
Background Reference 4:
Shiffman, D., et al. Arterioscler. Thromb. Vasc. Biol. 28(1):173-179(2008)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-955

List Size:
400 ul

List Price:

$495.00

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